HIGHLIGHTED TOPIC Skeletal and Cardiac Muscle Blood Flow Preclinical models of human peripheral arterial occlusive disease: implications for investigation of therapeutic agents
نویسندگان
چکیده
Richard E. Waters, Ronald L. Terjung, Kevin G. Peters, and Brian H. Annex Division of Cardiology, Department of Medicine, Durham Department of Veterans Affairs and Duke University Medical Center, Durham, North Carolina 27705; Department of Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, Missouri 65212; and Procter and Gamble Pharmaceuticals, Mason, Ohio 45069
منابع مشابه
Preclinical models of human peripheral arterial occlusive disease: implications for investigation of therapeutic agents.
Peripheral arterial occlusive disease (PAOD) is now recognized as a combination of clinical syndromes that are associated with significant morbidity and mortality. The primary pathophysiology of PAOD is impaired perfusion to the lower extremity. Effective pharmacotherapy designed to increase perfusion in PAOD is lacking, and revascularization options are suboptimal. New and more efficacious the...
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Objective: Assuming that cardiac rehabilitation and exercise significantly reduces mortality rate in coronary artery disease and has an important role in secondary prevention, the purpose of this study is to assess the effects of strength training and cardiac rehabilitation programs on biomechanical parameters of blood flow velocity and blood flow rate and these relationships with the brachial ...
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